Introduction: The involvement of the heart in respira-tory disorders aggravates disease progression and pro-gnosis, modifying the therapeutic approach. The main etiologic substrate of rhythm disorders in bronchial ob-structive syndrome is represented by hypoxic pulmo-nary vasoconstriction. Pharmacological strategies aim at supporting vital functions, diminishing symptoms, controlling risk factors, improving the quality of life and preventing future complications.
Methods: We present the case of a 67-year-old patient diagnosed with persistent atrial fibrillation and GOLD stage 3 COPD in a previous assessment, neglect the-rapeutically, hospitalized in a particularly serious con-dition with decompensated heart failure and bronchial asthma on the background of therapeutic incompliance and chronic consumption of ethanol, at a person with multiple chronic conditions.
Results: The investigations performed objectified chro-nic bronchitis affection and severe obstruction, coexis-ting with cardiac stasis by mixed cardiac, atherosclero-tic, ethanolic, and chronic hepatic lesions with hypers-plenism. Dynamic electrocardiographic monitoring re-vealed atrial fibrillation with AV ≈ 160/min alternating with unsupported ventricular tachycardia and frequent polymorphic ventricular extrasystoles systemized in doublets, expression of instability of coronary ische-mia. Under sustained treatment, the control of the acu-te bronchial infestation process and the improvement of the heart condition was achieved, with reinstallation of the sinus rhythm on the 13^th day of hospitalization. Concomitantly, the patient associates chronic kidney disease with ischemic nephropathy.
Conclusions: Cardio-respiratory disorders have com-mon pathophysiological mechanisms, which are based on the inflammatory process and endothelial dysfunc-tion. Patients with chronic lung disease require regular cardiac screening even in the absence of symptoms. Es-tablishing therapeutic behavior is a permanent challen-ge and requires a multidisciplinary approach.