Introduction: Heart failure (HF) syndrome is defined by the heart\’s inability to produce cardiac output syste-mic or pulmonary for tissue needs or to support it un-der increased filling pressures. The purpose. Studying Heart Failure Syndrome management in Children Ba-sed on the ISHLT Guide, (publication year 2014).
Methods: The article is based on the ISHLT Guidebook (2014), as well as medical publications from internatio-nal literature, and online material.
Results: HR causes are divided into cardiac and extra-cardiac. The cardiac causes are structural abnormalities cardiac overload, left-right shunt, pressure overload, valvular insufficiency, but may also be „normal“ in the regular heart – primary and secondary cardiomyo-pathy. Typical clinical manifestations in children may be tachypnea, alimentation problems (reflux, vomiting, loss of appetite), diaphoresis, and palpitations. The pa-raclinical evaluation includes routine analyzes and NT-proBNP, BNP, CK, MB fractions, cardiac troponins, C-reactive protein and functional and interventional tests (ECG standard 12 derivates, thoracic radiography + ICT, Echocardiography, Doppler-EcoCG ). Treat-ment of acute HF includes diuretics, inotropic therapy, milrinone, dobutamine, epinephrine, digoxin, systemic vasodilators. Chronic HF therapy includes IECA – cap-topril, enalapril, ramipril, perindopril, angiotensin II receptor antagonists – losartan, beta – blockers, aldost-erone antagonists.
Conclusions: The key to achieving therapeutic success and implicitly the survival of the pediatric patient is the appreciation and treatment of the HF cause and gradu-al introduction of drug therapy according to the seve-rity of clinical and paraclinical data.