Introduction: Pulmonary embolism (PE) is a severe disease, it is an important cause of morbidity and mortality, representing the third cause of death after myocardial infarction and stroke. Cancer is a well-known cause of PE.

Objective: To identify early death predictors in pati-ents with cancer and pulonary embolism and clinic and paraclinic patients caracteristics.

Methods: We analyzed prospectively a sample of 120 patients diagnosed with PE, admitted to our clinic („Sf. Pantelimon“ hospital, Bucharest) in the period november 2014 – March 2019. We compared clinical and paraclinical profile of patients with PE and with or witho-ut cancer.

Results: the mean age was of 68 ± 13.2 years, out of whi-ch 64% were female. 22% of these patients had associ-ated cancer with different locations. The most frequent type of malignacies were breast cancer, lung cancer and hematologic malignacies. We did not identify differen-ces between the ways in the emergency room between the groups analyzed. On the biological samples the mi-nimum value of the hemoglobin was lower in the case of the cancer patients. (Hgb medie 6.80 mg/dl vs. 7.90 mg/dl, p=0.05). Electrocardiographic, ecocardiogra-phic changes were similar in both groups, dysfunction of the right ventricle is not detected more frequently in the patients with PE and cancer. In- hospital mortality was 15%, similar between the two groups.

Conclusions: The association between PE and cancer is frequently common in current practice. Although in the group with PE and cancer have not identified a higher risk of mortality during hospitalization, we re-commend following their and individualization depen-ding on the risk of bleeding.